A meta-analysis of variability in conjunctival microvascular hemorheology metrics.
Sign Up to like & getrecommendations! Published in 2022 at "Microvascular research"
DOI: 10.1016/j.mvr.2022.104340
Abstract: Conjunctival hemorheology has been used analytically to assess qualities of blood flow associated with various forms of cardiovascular disorders including diabetes mellitus, stroke, and sickle cell disease. Although conjunctival axial red blood cell velocity (Vax)… read more here.
Keywords: healthy disease; disease state; disease; vax ... See more keywords
Are we failing clinical trials? A case for strong aggregate outcomes
Sign Up to like & getrecommendations! Published in 2017 at "Psychological Medicine"
DOI: 10.1017/s0033291717001726
Abstract: Clinical trials in psychiatry inherit methods for design and statistical analysis from evidence-based medicine. However, trials in other clinical disciplines benefit from a more specific relationship between instruments that measure disease state (e.g. biomarkers, clinical… read more here.
Keywords: disease state; medicine; clinical trials; failing clinical ... See more keywords
An evaluation of pharmacological options for Cushing’s disease: what are the state-of-the-art options?
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2023.2192349
Abstract: ABSTRACT Introduction Untreated Cushing’s syndrome (CS) is associated with significant morbidity and mortality. Cortisol normalization is a key goal to treatment. Pituitary surgery remains the first-line approach for Cushing’s disease, but sometimes it is impracticable,… read more here.
Keywords: evaluation pharmacological; disease; options cushing; disease state ... See more keywords
Dynamic modeling of hospitalized COVID-19 patients reveals disease state–dependent risk factors
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocac012
Abstract: Abstract Objective The study sought to investigate the disease state–dependent risk profiles of patient demographics and medical comorbidities associated with adverse outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Materials and Methods A… read more here.
Keywords: dependent risk; disease state; state; state dependent ... See more keywords
FRI0357 DRUG-INDUCED REMISSION AND SUBCLINICAL ACTIVITY IN PSORIATIC ARTHRITIS: TRANSCRIPTIONAL PROFILING TO CHARACTERIZETHE DISEASE STATE
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6936
Abstract: Background Remission is an important goal of therapy in psoriatic arthritis (PsA), but data on molecular players of clinical remission and effective disease inactivation are scarce. Gene expression profiling analysis could be useful to elucidate… read more here.
Keywords: disease state; analysis; remission; disease ... See more keywords
Pharmacogenomics in Stroke and Cardiovascular Disease: State of the Art
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.122.037717
Abstract: There is considerable interindividual variability in the response to antiplatelet and anticoagulant therapies, and this variation may be attributable to genetic variants. There has been an increased understanding of the genetic architecture of stroke and… read more here.
Keywords: pharmacogenomics stroke; cardiovascular disease; disease state; state art ... See more keywords
Data-Driven Differential Diagnosis of Dementia Using Multiclass Disease State Index Classifier
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2018.00111
Abstract: Clinical decision support systems (CDSSs) hold potential for the differential diagnosis of neurodegenerative diseases. We developed a novel CDSS, the PredictND tool, designed for differential diagnosis of different types of dementia. It combines information obtained… read more here.
Keywords: disease state; state index; dementia; index classifier ... See more keywords
Identifying genes in Parkinson disease: state of the art
Sign Up to like & getrecommendations! Published in 2018 at "Medical Journal of Australia"
DOI: 10.5694/mja17.01254
Abstract: 381 P bradykinesia, movement rigidity and tremors in affected individuals. Our understanding of the genetic basis of PD has been steadily increasing since the initial report of a-synuclein mutations two decades ago. Mutations implicated in… read more here.
Keywords: genes parkinson; disease state; identifying genes; parkinson disease ... See more keywords