Sparse estimation for case-control studies with multiple disease subtypes.
Sign Up to like & getrecommendations! Published in 2020 at "Biostatistics"
DOI: 10.1093/biostatistics/kxz063
Abstract: The analysis of case-control studies with several disease subtypes is increasingly common, e.g. in cancer epidemiology. For matched designs, a natural strategy is based on a stratified conditional logistic regression model. Then, to account for… read more here.
Keywords: disease subtypes; case control; control studies;
Automated phenotyping of patients with non-alcoholic fatty liver disease reveals clinically relevant disease subtypes
Sign Up to like & getrecommendations! Published in 2020 at "Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing"
DOI: 10.1142/9789811215636_0009
Abstract: Non-alcoholic fatty liver disease (NAFLD) is a complex heterogeneous disease which affects more than 20% of the population worldwide. Some subtypes of NAFLD have been clinically identified using hypothesis-driven methods. In this study, we used… read more here.
Keywords: alcoholic fatty; fatty liver; non alcoholic; disease ... See more keywords
Genetic Influences on Disease Subtypes.
Sign Up to like & getrecommendations! Published in 2020 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-120319-095026
Abstract: Disease classification, or nosology, was historically driven by careful examination of clinical features of patients. As technologies to measure and understand human phenotypes advanced, so too did classifications of disease, and the advent of genetic… read more here.
Keywords: genetic influences; nosology; disease; disease subtypes ... See more keywords
Learning a Comorbidity-Driven Taxonomy of Pediatric Pulmonary Hypertension
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DOI: 10.1161/circresaha.117.310804
Abstract: Rationale: Pediatric pulmonary hypertension (PH) is a heterogeneous condition with varying natural history and therapeutic response. Precise classification of PH subtypes is, therefore, crucial for individualizing care. However, gaps remain in our understanding of the… read more here.
Keywords: pediatric pulmonary; pulmonary hypertension; network; comorbidity ... See more keywords