Phenomics and Robust Multiomics Data for Cardiovascular Disease Subtyping.
Sign Up to like & getrecommendations! Published in 2023 at "Arteriosclerosis, thrombosis, and vascular biology"
DOI: 10.1161/atvbaha.122.318892
Abstract: The complex landscape of cardiovascular diseases encompasses a wide range of related pathologies arising from diverse molecular mechanisms and exhibiting heterogeneous phenotypes. This variety of manifestations poses significant challenges in the development of treatment strategies.… read more here.
Keywords: multiomics data; phenomics robust; disease subtyping; cardiovascular disease ... See more keywords
Developing automated methods for disease subtyping in UK Biobank: an exemplar study on stroke
Sign Up to like & getrecommendations! Published in 2021 at "BMC Medical Informatics and Decision Making"
DOI: 10.1186/s12911-021-01556-0
Abstract: Background Better phenotyping of routinely collected coded data would be useful for research and health improvement. For example, the precision of coded data for hemorrhagic stroke (intracerebral hemorrhage [ICH] and subarachnoid hemorrhage [SAH]) may be… read more here.
Keywords: disease subtyping; biobank; radiology; automated methods ... See more keywords
Subtyping of Parkinson’s Disease - Where Are We Up To?
Sign Up to like & getrecommendations! Published in 2019 at "Aging and Disease"
DOI: 10.14336/ad.2019.0112
Abstract: Heterogenous clinical presentations of Parkinson’s disease have aroused several attempts in its subtyping for the purpose of strategic implementation of treatment in order to maximise therapeutic effects. Apart from a priori classifications based purely on… read more here.
Keywords: subtyping parkinson; cluster analysis; parkinson disease; disease ... See more keywords
A Sparse Mixture-of-Experts Model With Screening of Genetic Associations to Guide Disease Subtyping
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.859462
Abstract: Motivation: Identifying new genetic associations in non-Mendelian complex diseases is an increasingly difficult challenge. These diseases sometimes appear to have a significant component of heritability requiring explanation, and this missing heritability may be due to… read more here.
Keywords: disease subtyping; disease; sparse mixture; genetic associations ... See more keywords
Parkinson’s Disease Subtyping Using Clinical Features and Biomarkers: Literature Review and Preliminary Study of Subtype Clustering
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12010112
Abstract: The second most common progressive neurodegenerative disorder, Parkinson’s disease (PD), is characterized by a broad spectrum of symptoms that are associated with its progression. Several studies have attempted to classify PD according to its clinical… read more here.
Keywords: medicine; disease subtyping; using clinical; clinical features ... See more keywords