The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-018-0716-7
Abstract: Sex differences in immunity are well described in the literature and thought to be mainly driven by sex hormones and sex-linked immune response genes. The gastrointestinal tract (GIT) is one of the largest immune organs… read more here.
Keywords: sex differences; sex; disease susceptibility; immunity disease ... See more keywords
Individual and joint effects of genetic polymorphisms in microRNA-machinery genes on congenital heart disease susceptibility.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiology in the young"
DOI: 10.1017/s1047951120004874
Abstract: Single-nucleotide polymorphisms in miRNA-machinery genes may alter the biogenesis of miRNAs affecting disease susceptibility. In this case-control study, we aimed to evaluate the impact of three single-nucleotide polymorphisms (DICER rs1057035, DROSHA rs10719, and XPO5 rs11077)… read more here.
Keywords: chd; machinery genes; disease susceptibility; risk ... See more keywords
Microbial dysbiosis reflects disease resistance in diverse coral species
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-02163-5
Abstract: Disease outbreaks have caused significant declines of keystone coral species. While forecasting disease outbreaks based on environmental factors has progressed, we still lack a comparative understanding of susceptibility among coral species that would help predict… read more here.
Keywords: coral species; disease susceptibility; disease; microbial dysbiosis ... See more keywords
Variation in plant Toll/Interleukin-1 receptor domain protein dependence on ENHANCED DISEASE SUSCEPTIBILITY 1
Sign Up to like & getrecommendations! Published in 2022 at "Plant Physiology"
DOI: 10.1093/plphys/kiac480
Abstract: Abstract Toll/Interleukin-1 receptor (TIR) domains are integral to immune systems across all kingdoms. In plants, TIRs are present in nucleotide-binding leucine-rich repeat (NLR) immune receptors, NLR-like, and TIR-only proteins. Although TIR-NLR and TIR signaling in… read more here.
Keywords: tir; toll interleukin; enhanced disease; disease susceptibility ... See more keywords
Glutathione S‐transferase genes and the risk of type 2 diabetes mellitus: Role of sexual dimorphism, gene–gene and gene–smoking interactions in disease susceptibility
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.12623
Abstract: Compromised defense against reactive oxygen species (ROS) is considered important in the pathogenesis of type 2 diabetes mellitus (T2DM); therefore, genes encoding antioxidant defense enzymes may contribute to disease susceptibility. This study investigated whether polymorphisms… read more here.
Keywords: type diabetes; diabetes mellitus; gene gene; glutathione transferase ... See more keywords
Physical and Mental Activity, Disease Susceptibility, and Risk of Dementia
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200701
Abstract: Background and Objectives The association between patterns of physical/mental activity and dementia and how it is affected by disease susceptibility remains unknown. We aimed to examine the association between patterns of physical and mental activity… read more here.
Keywords: physical mental; mental activity; activity; disease susceptibility ... See more keywords
Interactive Regulation of Hormone and Resistance Gene in Proline Metabolism Is Involved in Effector-Triggered Immunity or Disease Susceptibility in the Xanthomonas campestris pv. campestris–Brassica napus Pathosystem
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.738608
Abstract: To characterize cultivar variations in hormonal regulation of the transition between pattern-triggered immunity (PTI) and effector-triggered immunity or susceptibility (ETI or ETS), the responses of resistance (R-) genes, hydrogen peroxide, and proline metabolism in two… read more here.
Keywords: triggered immunity; disease; disease susceptibility; proline metabolism ... See more keywords
Untangling the immune basis of disease susceptibility
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.56886
Abstract: Interactions between immune cell receptors and proteins that determine disease susceptibility shed light on how different arms of the immune system are involved in three viral infections and Crohn's disease. read more here.
Keywords: untangling immune; immune basis; basis disease; disease ... See more keywords
Symbiotic immuno-suppression: is disease susceptibility the price of bleaching resistance?
Sign Up to like & getrecommendations! Published in 2018 at "PeerJ"
DOI: 10.7717/peerj.4494
Abstract: Accelerating anthropogenic climate change threatens to destroy coral reefs worldwide through the processes of bleaching and disease. These major contributors to coral mortality are both closely linked with thermal stress intensified by anthropogenic climate change.… read more here.
Keywords: symbiotic immuno; bleaching disease; disease; immuno suppression ... See more keywords