The Link Between Tau and Insulin Signaling: Implications for Alzheimer’s Disease and Other Tauopathies
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00017
Abstract: The microtubule-associated protein tau (MAPT) is mainly identified as a tubulin binding protein essential for microtubule dynamics and assembly and for neurite outgrowth. However, several other possible functions for Tau remains to be investigated. Insulin… read more here.
Keywords: insulin; disease tauopathies; alzheimer disease; pathology ... See more keywords
Tau Protein Interaction Partners and Their Roles in Alzheimer’s Disease and Other Tauopathies
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DOI: 10.3390/ijms22179207
Abstract: Tau protein plays a critical role in the assembly, stabilization, and modulation of microtubules, which are important for the normal function of neurons and the brain. In diseased conditions, several pathological modifications of tau protein… read more here.
Keywords: alzheimer disease; tau protein; disease tauopathies; interaction partners ... See more keywords
Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer’s Disease and Other Tauopathies
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032161
Abstract: Alzheimer’s disease and other tauopathies are the world’s leading causes of dementia and memory loss. These diseases are thought to be caused by the misfolding and aggregation of the intracellular tau protein, ultimately leading to… read more here.
Keywords: tau protein; alzheimer disease; disease tauopathies; tau ... See more keywords