Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2118818119
Abstract: Significance To date, no cure or preventative treatment for Parkinson’s disease (PD) has yet been developed. Here, we show that kurarinone, a natural flavonoid, alleviated parkinsonism-like symptoms induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Using a… read more here.
Keywords: disease via; kurarinone alleviated; disease; parkinson disease ... See more keywords
Exosomes: Potential Therapies for Disease via Regulating TLRs
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DOI: 10.1155/2020/2319616
Abstract: Exosomes are small membrane vesicles that retain various substances such as proteins, nucleic acids, and small RNAs. Exosomes play crucial roles in many physiological and pathological processes, including innate immunity. Innate immunity is an important… read more here.
Keywords: immunity; exosomes potential; disease via; therapies disease ... See more keywords
Cornuside Is a Potential Agent against Alzheimer’s Disease via Orchestration of Reactive Astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14153179
Abstract: Cornuside is an iridoid glycoside from Cornus officinalis, with the activities of anti-inflammatory, antioxidant, anti-mitochondrial dysfunction, and neuroprotection. In the present research, a triple-transgenic mice model of AD (3 × Tg-AD) was used to explore… read more here.
Keywords: akt nrf2; alzheimer disease; agent alzheimer; potential agent ... See more keywords