Modelling neurodegenerative diseases with 3D brain organoids
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DOI: 10.1111/brv.12626
Abstract: Neurodegenerative diseases are incurable and debilitating conditions characterized by the deterioration of brain function. Most brain disease models rely on human post‐mortem brain tissue, non‐human primate tissue, or in vitro two‐dimensional (2D) experiments. Resource limitations… read more here.
Keywords: diseases brain; disease; neurodegenerative diseases; modelling neurodegenerative ... See more keywords
Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging
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DOI: 10.4103/1673-5374.264444
Abstract: Interleukin-1β is a potent proinflammatory cytokine that plays a key role in the pathogenesis of the brain aging and diverse range of neurological diseases including Alzheimer’s disease, Parkinson’s disease, stroke and persistent pain. Activated microglia… read more here.
Keywords: diseases brain; cathepsin; inflammatory brain; brain diseases ... See more keywords