Epigenetic modifications of Klotho expression in kidney diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular medicine"
DOI: 10.1007/s00109-021-02044-8
Abstract: Developments of many renal diseases are substantially influenced by epigenetic modifications of numerous genes, mainly mediated by DNA methylations, histone modifications, and microRNA interference; however, not all gene modifications causally affect the disease onset or… read more here.
Keywords: modifications klotho; epigenetic modifications; kidney diseases; expression kidney ... See more keywords
Rare diseases of epigenetic origin: Challenges and opportunities
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1113086
Abstract: Rare diseases (RDs), more than 80% of which have a genetic origin, collectively affect approximately 350 million people worldwide. Progress in next-generation sequencing technology has both greatly accelerated the pace of discovery of novel RDs… read more here.
Keywords: epigenetic origin; diseases epigenetic; rare diseases; challenges opportunities ... See more keywords