Deciphering the roles of caveolin in neurodegenerative diseases: The good, the bad and the importance of context
Sign Up to like & getrecommendations! Published in 2020 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2020.101116
Abstract: Neurodegenerative diseases (NDDs), which contribute to progressive and irreversible impairments of both the structure and function of the nervous system, pose a substantial socioeconomic burden on society. Mitochondrial dysfunction, oxidative stress, membrane damage, DNA damage,… read more here.
Keywords: roles caveolin; diseases good; caveolin neurodegenerative; good bad ... See more keywords
Checkpoint Inhibition and Infectious Diseases: A Good Thing?
Sign Up to like & getrecommendations! Published in 2019 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2019.08.004
Abstract: The mammalian immune system has evolved the capacity to detect and destroy tumor cells. Tumors utilize multiple strategies to evade host immune surveillance, including the induction of the checkpoint molecules cytotoxic T lymphocyte-associated protein 4… read more here.
Keywords: diseases good; infectious diseases; inhibition infectious; good thing ... See more keywords
Granzymes in health and diseases: the good, the bad and the ugly
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1371743
Abstract: Granzymes are a family of serine proteases, composed of five human members: GA, B, H, M and K. They were first discovered in the 1980s within cytotoxic granules released during NK cell- and T cell-mediated… read more here.
Keywords: health diseases; bad ugly; granzymes health; cell ... See more keywords