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Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21093369

Abstract: Cells have developed elaborate quality-control mechanisms for proteins and organelles to maintain cellular homeostasis. Such quality-control mechanisms are maintained by conformational folding via molecular chaperones and by degradation through the ubiquitin-proteasome or autophagy-lysosome system. Accumulating… read more here.

Keywords: autophagy neurodegenerative; disease; neurodegenerative diseases; diseases hunter ... See more keywords