Primary mitochondrial diseases: The intertwined pathophysiology of bioenergetic dysregulation, oxidative stress and neuroinflammation
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DOI: 10.1111/eci.14217
Abstract: Primary mitochondrial diseases (PMDs) are rare genetic disorders resulting from mutations in genes crucial for effective oxidative phosphorylation (OXPHOS) that can affect mitochondrial function. In this review, we examine the bioenergetic alterations and oxidative stress… read more here.
Keywords: primary mitochondrial; oxidative stress; stress neuroinflammation; mitochondrial diseases ... See more keywords