Aging and age‐related diseases: from mechanisms to therapeutic strategies
Sign Up to like & getrecommendations! Published in 2021 at "Biogerontology"
DOI: 10.1007/s10522-021-09910-5
Abstract: Aging is a physiological process mediated by numerous biological and genetic pathways, which are directly linked to lifespan and are a driving force for all age-related diseases. Human life expectancy has greatly increased in the… read more here.
Keywords: diseases mechanisms; mechanisms therapeutic; aging age; age related ... See more keywords
δ-secretase in neurodegenerative diseases: mechanisms, regulators and therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2020 at "Translational Neurodegeneration"
DOI: 10.1186/s40035-019-0179-3
Abstract: Mammalian asparagine endopeptidase (AEP) is a cysteine protease that cleaves its protein substrates on the C-terminal side of asparagine residues. Converging lines of evidence indicate that AEP may be involved in the pathogenesis of several… read more here.
Keywords: diseases mechanisms; secretase neurodegenerative; regulators therapeutic; neurodegenerative diseases ... See more keywords
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032706
Abstract: Coffee is one of the most widely consumed beverages worldwide, and epidemiology studies associate higher coffee consumption with decreased rates of mortality and decreased rates of neurological and metabolic diseases, including Parkinson’s disease and type… read more here.
Keywords: coffee; coffee consumption; health benefits; diseases mechanisms ... See more keywords
Gut Molecules in Cardiometabolic Diseases: The Mechanisms behind the Story
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043385
Abstract: Atherosclerotic cardiovascular disease is the most common cause of morbidity and mortality worldwide. Diabetes mellitus increases cardiovascular risk. Heart failure and atrial fibrillation are associated comorbidities that share the main cardiovascular risk factors. The use… read more here.
Keywords: mechanisms behind; behind story; diseases mechanisms; molecules cardiometabolic ... See more keywords