MiRNA Biogenesis and Regulation of Diseases: An Overview.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6524-3_1
Abstract: MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to target mRNAs. Since it was discovered in 1993, miRNA are found in all eukaryotic cells conserved across… read more here.
Keywords: biogenesis regulation; mirna biogenesis; biology; regulation diseases ... See more keywords
Multiparametric ultrasound in liver diseases: an overview for the practising clinician
Sign Up to like & getrecommendations! Published in 2019 at "Postgraduate Medical Journal"
DOI: 10.1136/postgradmedj-2018-136111
Abstract: Ultrasound (US) is usually the first and most commonly used tool in the diagnostic algorithm for liver disease. It is widely available, non-invasive and offers a real-time assessment of the liver in several anatomic planes,… read more here.
Keywords: ultrasound liver; multiparametric ultrasound; overview practising; liver diseases ... See more keywords
Indazole and its derivatives in cardiovascular diseases: Overview, current scenario and future perspectives.
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026621666211214151534
Abstract: Indazoles are a class of heterocyclic compounds with a bicyclic ring structure composed of a pyrazole ring and a benzene ring. Indazole-containing compounds with various functional groups have important pharmacological activities and can be used… read more here.
Keywords: current scenario; indazole derivatives; derivatives cardiovascular; cardiovascular diseases ... See more keywords
Polyphenols and Their Metabolites in Renal Diseases: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11071060
Abstract: Kidney diseases constitute a worldwide public health problem, contributing to morbidity and mortality. The present study aimed to provide an overview of the published data regarding the potential beneficial effects of polyphenols on major kidney… read more here.
Keywords: diseases overview; kidney; renal diseases; effects polyphenols ... See more keywords
Impairment of Mitochondrial Respiration in Metabolic Diseases: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23168852
Abstract: Mitochondrial dysfunction has emerged as a central pathomechanism in the setting of obesity and diabetes mellitus, linking these intertwined pathologies that share insulin resistance as a common denominator. High-resolution respirometry (HRR) is a state-of-the-art research… read more here.
Keywords: respiration metabolic; diseases overview; metabolic diseases; respiration ... See more keywords
A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231710014
Abstract: Histone deacetylases (HDACs) are epigenetic enzymes which participate in transcriptional repression and chromatin condensation mechanisms by removing the acetyl moiety from acetylated ε-amino group of histone lysines and other non-histone proteins. In recent years, HDAC8,… read more here.
Keywords: hdac8; perspective hdac8; diseases overview; different diseases ... See more keywords
Vaccines against Emerging and Neglected Infectious Diseases: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10091385
Abstract: Neglected Tropical Diseases (NTDs) are a group of diseases that are highly prevalent in tropical and subtropical regions, and closely associated with poverty and marginalized populations. Infectious diseases affect over 1.6 billion people annually, and… read more here.
Keywords: infectious diseases; diseases overview; vaccines emerging; emerging neglected ... See more keywords