Modeling Lysosomal Storage Diseases in the Zebrafish
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.00082
Abstract: Lysosomal storage diseases (LSDs) are a family of 70 metabolic disorders characterized by mutations in lysosomal proteins that lead to storage material accumulation, multiple-organ pathologies that often involve neurodegeneration, and early mortality in a significant… read more here.
Keywords: modeling lysosomal; storage; lysosomal storage; etiology ... See more keywords
Modeling neuromuscular diseases in zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1054573
Abstract: Neuromuscular diseases are a diverse group of conditions that affect the motor system and present some overlapping as well as distinct clinical manifestations. Although individually rare, the combined prevalence of NMDs is similar to Parkinson’s.… read more here.
Keywords: modeling neuromuscular; diseases zebrafish; neuromuscular diseases;
The Zebrafish Model to Understand Epigenetics in Renal Diseases
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22179152
Abstract: Epigenetic modifications are able to alter gene expression and include DNA methylation, different histone variants, and post-transcriptional modifications (PTMs), such as acetylation or phosphorylation, and through short/long RNAs, respectively. In this review, we focus on… read more here.
Keywords: epigenetic modifications; epigenetics renal; renal diseases; zebrafish model ... See more keywords