Bioequivalence of Esaxerenone Conventional Tablet and Orally Disintegrating Tablet: Two Single‐Dose Crossover Studies in Healthy Japanese Men
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1087
Abstract: We assessed the bioequivalence of a single dose of 5‐mg of esaxerenone administered as an orally disintegrating tablet (ODT) with the conventional oral tablet in healthy Japanese men. This single‐center, open‐label, randomized, two‐drug, two‐stage crossover,… read more here.
Keywords: single dose; orally disintegrating; tablet; disintegrating tablet ... See more keywords
Orally disintegrating dosage forms
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-018-0408-2
Abstract: An orally disintegrating tablet is a novel formulation that dissolves in the saliva within a few seconds and without requiring of drinking additional water. This dosage form is a powerful way to deliver active drugs… read more here.
Keywords: orally disintegrating; disintegrating dosage; dosage forms; disintegrating tablet ... See more keywords
Fast disintegrating tablet of Doxazosin Mesylate nanosuspension: Preparation and characterization
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102210
Abstract: ABSTRACT Doxazosin Mesylate (DOX) is an antihypertensive drug which possesses poor water solubility and hence low bioavailability. The study objective is to prepare DOX fast disintegrating tablets as a new dosage form for geriatric patients.… read more here.
Keywords: disintegrating tablet; nanosuspension; fast disintegrating; doxazosin mesylate ... See more keywords
Efficacy, safety, and tolerability of rimegepant orally disintegrating tablet for the acute treatment of migraine: a randomised, phase 3, double-blind, placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "The Lancet"
DOI: 10.1016/s0140-6736(19)31606-x
Abstract: BACKGROUND Rimegepant, a small molecule calcitonin gene-related peptide receptor antagonist, has shown efficacy in the acute treatment of migraine using a standard tablet formulation. The objective of this trial was to compare the efficacy, safety,… read more here.
Keywords: disintegrating tablet; placebo; treatment; migraine ... See more keywords
Development and optimization of a meloxicam/β-cyclodextrin complex for orally disintegrating tablet using statistical analysis
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2016.1264418
Abstract: Abstract The purpose of this research was to develop an inclusion complex of meloxicam (MEL)/β-cyclodextrin (β-CD) incorporated into an orally disintegrating tablet (ODT), using statistical analysis to optimize the ODT formulation based on a quality… read more here.
Keywords: orally disintegrating; analysis; meloxicam; statistical analysis ... See more keywords