A Disintegrin and Metalloprotease 10 Expressions Modulate Potential Metastatic and Thrombus Formation in Pancreatic Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v51i8.10262
Abstract: Background: Clinical investigations repurposing a disintegrin and metalloproteases 10 (ADAM10) as metastatic and thrombus marker have achieved encouraging results, but the mechanism behind this association remains unclear. Methods: This study was carried out in NingXia… read more here.
Keywords: adam10 expression; pancreatic carcinoma; thrombus formation; thrombus ... See more keywords
Improved Antithrombotic Activity and Diminished Bleeding Side Effect of a PEGylated αIIbβ3 Antagonist, Disintegrin
Sign Up to like & getrecommendations! Published in 2020 at "Toxins"
DOI: 10.3390/toxins12070426
Abstract: Polymer polyethylene glycol (PEG), or PEGylation of polypeptides improves protein drug stability by decreasing degradation and reducing renal clearance. To produce a pharmaceutical disintegrin derivative, the N-terminal PEGylation technique was used to modify the disintegrin… read more here.
Keywords: side effect; disintegrin; activity; peg ... See more keywords
Molecular characterization and expression of a disintegrin and metalloproteinase with thrombospondin motifs 8 in chicken
Sign Up to like & getrecommendations! Published in 2018 at "Asian-Australasian Journal of Animal Sciences"
DOI: 10.5713/ajas.18.0265
Abstract: Objective A disintegrin and metallopeptidase with thrombospondin motifs type 8 (ADAMTS8) is crucial for diverse physiological processes, such as inflammation, tissue morphogenesis, and tumorigenesis. The chicken ADAMTS8 (chADAMTS8) gene was differentially expressed in the kidney… read more here.
Keywords: thrombospondin motifs; disintegrin; expression; gene ... See more keywords