Induction of Cu/Zn Superoxide Dismutase (SOD1) Aggregation in Living Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8820-4_13
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive degeneration and loss of motor neurons that appears to spread through the neuroaxis in a spatiotemporally restricted manner. In the familial form of… read more here.
Keywords: aggregation; sod1; dismutase sod1; living cells ... See more keywords
Cu/Zn Superoxide Dismutase (Sod1) regulates the canonical Wnt signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.11.011
Abstract: Cu/Zn Superoxide Dismutase (Sod1) catalyzes the disproportionation of cytotoxic superoxide radicals (O2•-) into oxygen (O2) and hydrogen peroxide (H2O2), a key signaling molecule. In Saccharomyces cerevisiae, we previously discovered that Sod1 participates in an H2O2-mediated… read more here.
Keywords: wnt signaling; sod1; dismutase sod1; signaling pathway ... See more keywords
Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS)
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2020.1738390
Abstract: ABSTRACT Introduction: Amyotrophic lateral sclerosis (ALS) is a progressive and incurable neurodegenerative disorder that targets upper and lower motor neurons and leads to fatal muscle paralysis. Mutations in the superoxide dismutase 1 (SOD1) gene are… read more here.
Keywords: sod1; lateral sclerosis; dismutase sod1; amyotrophic lateral ... See more keywords
The identification of high-performing antibodies for Superoxide dismutase [Cu-Zn] 1 (SOD1) for use in Western blot, immunoprecipitation, and immunofluorescence
Sign Up to like & getrecommendations! Published in 2023 at "F1000Research"
DOI: 10.12688/f1000research.132952.1
Abstract: Superoxide dismutase [Cu-Zn] 1 (SOD1), is an antioxidant enzyme encoded by the gene SOD1, responsible for regulating oxidative stress levels by sequestering free radicals. Identified as the first gene with mutations in Amyotrophic lateral sclerosis… read more here.
Keywords: blot immunoprecipitation; superoxide dismutase; dismutase sod1; immunoprecipitation immunofluorescence ... See more keywords