QUARTERplus: Accurate disorder predictions integrated with interpretable residue-level quality assessment scores
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.04.066
Abstract: A recent advance in the disorder prediction field is the development of the quality assessment (QA) scores. QA scores complement the propensities produced by the disorder predictors by identifying regions where these predictions are more… read more here.
Keywords: disorder predictions; disorder; residue level; quality assessment ... See more keywords
Analysis of Protein Disorder Predictions in the Light of a Protein Structural Alphabet
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DOI: 10.3390/biom10071080
Abstract: Intrinsically-disordered protein (IDP) characterization was an amazing change of paradigm in our classical sequence-structure-function theory. Moreover, IDPs are over-represented in major disease pathways and are now often targeted using small molecules for therapeutic purposes. This… read more here.
Keywords: protein; analysis; disorder; structural alphabet ... See more keywords
Comparative Assessment of Intrinsic Disorder Predictions with a Focus on Protein and Nucleic Acid-Binding Proteins
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DOI: 10.3390/biom10121636
Abstract: With over 60 disorder predictors, users need help navigating the predictor selection task. We review 28 surveys of disorder predictors, showing that only 11 include assessment of predictive performance. We identify and address a few… read more here.
Keywords: binding proteins; disorder; assessment intrinsic; disorder predictions ... See more keywords