Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.05.046
Abstract: Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding the genetic factors contributing to the shared and disorder-specific symptoms will be crucial for improving diagnosis and treatment. In genetic data consisting of… read more here.
Keywords: genomic dissection; disorder; bipolar disorder; disorder schizophrenia ... See more keywords
Anatomical dysconnectivity in bipolar disorder compared with schizophrenia: A selective review of structural network analyses using diffusion MRI.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2016.11.015
Abstract: BACKGROUND The dysconnectivity hypothesis suggests that psychotic illnesses arise not from regionally specific focal pathophysiology, but rather from impaired neuroanatomical integration across networks of brain regions. Decreased white matter organization has been hypothesized to be… read more here.
Keywords: dysconnectivity; diffusion; disorder; psychotic illnesses ... See more keywords
Calcium as a Trojan horse in mental diseases—The role of PMCA and PMCA-interacting proteins in bipolar disorder and schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.08.005
Abstract: Although first mentions about calcium disturbances in psychiatric diseases appeared more than 30 years ago, the most recent genomic and proteomic findings confirmed a significant role of Ca2+ and Ca2+-regulated pathways in development of neuropathological… read more here.
Keywords: pmca; role; ca2; disorder schizophrenia ... See more keywords
Mini-review: Brain energy metabolism and its role in animal models of depression, bipolar disorder, schizophrenia and autism
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136003
Abstract: Mitochondria are cellular organelles essential for energy metabolism and antioxidant defense. Mitochondrial impairment is implicated in many psychiatric disorders, including depression, bipolar disorder, schizophrenia, and autism. To characterize and eventually find effective treatments of bioenergetic… read more here.
Keywords: depression bipolar; schizophrenia autism; bipolar disorder; disorder schizophrenia ... See more keywords
Distinct temporal brain dynamics in bipolar disorder and schizophrenia during emotion regulation
Sign Up to like & getrecommendations! Published in 2019 at "Psychological Medicine"
DOI: 10.1017/s0033291719000217
Abstract: Abstract Background Disturbances in emotion regulation (ER) are characteristic of both patients with bipolar disorder (BD) and schizophrenia (SZ). We investigated the temporal dynamics of brain activation during cognitive ER in BD and SZ to… read more here.
Keywords: emotion regulation; disorder schizophrenia; regulation; bipolar disorder ... See more keywords
Prevalence of smoking in patients with bipolar disorder, major depressive disorder and schizophrenia and their relationships with quality of life
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07928-9
Abstract: Few studies have compared the prevalence of smoking between patients with bipolar disorder, major depressive disorder (MDD) and schizophrenia. This study examined the prevalence of smoking and its relationships with demographic and clinical characteristics, and… read more here.
Keywords: disorder; prevalence smoking; bipolar disorder; disorder schizophrenia ... See more keywords
Thought Disorder in Schizophrenia and Bipolar Disorder Probands, Their Relatives, and Nonpsychiatric Controls
Sign Up to like & getrecommendations! Published in 2017 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx016
Abstract: Thought disorder (TD) has long been associated with schizophrenia (SZ) and is now widely recognized as a symptom of mania and other psychotic disorders as well. Previous studies have suggested that the TD found in… read more here.
Keywords: disorder; nonpsychiatric controls; thought disorder; bipolar disorder ... See more keywords
In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN
Sign Up to like & getrecommendations! Published in 2019 at "eNeuro"
DOI: 10.1523/eneuro.0403-18.2019
Abstract: Visual Abstract Bipolar disorder (BP) and schizophrenia (SCZ) are major psychiatric disorders, but the molecular mechanisms underlying the complicated pathologies of these disorders remain unclear. It is difficult to establish adequate in vitro models for… read more here.
Keywords: pluripotent stem; disorder schizophrenia; copy number; stem cells ... See more keywords
Resilience and its relationship with disability in persons with bipolar disorder and schizophrenia: A comparative study
Sign Up to like & getrecommendations! Published in 2023 at "Indian Journal of Psychiatry"
DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_238_22
Abstract: ABSTRACT Background: Resilience is the capacity to bounce back from adversity. Severe mental illnesses are associated with poor and heterogeneous functional outcomes. Symptom remission is inadequate to achieve patient-oriented outcome, and positive psychopathology constructs like… read more here.
Keywords: resilience; disability; bipolar disorder; disorder schizophrenia ... See more keywords