Recognition Mechanisms between a Nanobody and Disordered Epitopes of the Human Prion Protein: An Integrative Molecular Dynamics Study
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DOI: 10.1021/acs.jcim.2c01062
Abstract: Immunotherapy using antibodies to target the aggregation of flexible proteins holds promise for therapeutic interventions in neurodegenerative diseases caused by protein misfolding. Prions or PrPSc, the causal agents of transmissible spongiform encephalopathies (TSE), represent a… read more here.
Keywords: recognition; human prion; recognition mechanisms; disordered epitopes ... See more keywords