Temperature-sensitive contacts in disordered loops tune enzyme I activity
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1101/2022.06.18.496683
Abstract: Homologous enzymes with identical folds often exhibit different thermal and kinetic behaviors. Understanding how enzyme sequence encodes catalytic activity at functionally optimal temperatures is a fundamental problem in biophysics. Recently it was shown that the… read more here.
Keywords: enzyme activity; temperature; disordered loops; activity ... See more keywords