Molecular landscape of long noncoding RNAs in brain disorders
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DOI: 10.1038/s41380-020-00947-5
Abstract: According to current paradigms, various risk factors, such as genetic mutations, oxidative stress, neural network dysfunction, and abnormal protein degradation, contribute to the progression of brain disorders. Through the cooperation of gene transcripts in biological… read more here.
Keywords: long noncoding; brain disorders; molecular landscape; noncoding rnas ... See more keywords
Lysosomal Storage Disorders: Molecular Basis and Therapeutic Approaches
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DOI: 10.3390/biom11070964
Abstract: Lysosomal storage disorders (LSDs) are a group of 60 rare inherited diseases characterized by a heterogeneous spectrum of clinical symptoms, ranging from severe intellectual disabilities, cardiac abnormalities, visceromegaly, and bone deformities to slowly progressive muscle… read more here.
Keywords: lysosomal storage; molecular basis; basis therapeutic; disorders molecular ... See more keywords
Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094764
Abstract: The therapeutic benefits of the current medications for patients with psychiatric disorders contrast with a great variety of adverse effects. The endocannabinoid system (ECS) components have gained high interest as potential new targets for treating… read more here.
Keywords: psychiatric disorders; endocannabinoid system; disorders molecular; alterations ecs ... See more keywords