A Novel Forming Method of Traditional Chinese Medicine Dispersible Tablets to Achieve Rapid Disintegration Based on the Powder Modification Principle
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28734-x
Abstract: Slow disintegration and poor solubility are common problems facing the dispersible tablets of Traditional Chinese Medicine (TCM). In an early study, the research group found that co-grinding of extracts and silica could achieve a rapid… read more here.
Keywords: medicine; disintegration; rapid disintegration; achieve rapid ... See more keywords
Co-Processed Excipients for Dispersible Tablets—Part 2: Patient Acceptability
Sign Up to like & getrecommendations! Published in 2018 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-018-1104-2
Abstract: Palatability and patient acceptability are critical attributes of dispersible tablet formulation. Co-processed excipients could provide improved organoleptic profile due to rational choice of excipients and manufacturing techniques. The aim of this study was to identify… read more here.
Keywords: acceptability; melt type; patient acceptability; processed excipients ... See more keywords
Insufficient Stability of Clavulanic Acid in Widely Used Child-Appropriate Formulations
Sign Up to like & getrecommendations! Published in 2021 at "Antibiotics"
DOI: 10.3390/antibiotics10020225
Abstract: Amoxicillin-clavulanic acid (AMC) belongs to the WHO Essential Medicines List for children, but for optimal antimicrobial effectiveness, reconstituted dry powder suspensions need to be stored in a refrigerated environment. Many patients in low- and middle-income… read more here.
Keywords: child appropriate; acid; clavulanic acid; appropriate formulations ... See more keywords
Design and Evaluation of Orally Dispersible Tablets Containing Amlodipine Inclusion Complexes in Hydroxypropyl-β-cyclodextrin and Methyl-β-cyclodextrin
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15155217
Abstract: The development of new orally dispersible tablets containing amlodipine (AML) inclusion complexes in hydroxypropyl-β-cyclodextrin (HP-β-CD) and in methyl-β-cyclodextrin (Me-β-CD) was studied. The methods of obtaining amlodipine and the physical and chemical properties of the inclusion… read more here.
Keywords: containing amlodipine; dispersible tablets; tablets containing; orally dispersible ... See more keywords