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Roles of surfactant and polymer in drug release from spray-dried hybrid nanocrystal-amorphous solid dispersions (HyNASDs)

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Published in 2020 at "Powder Technology"

DOI: 10.1016/j.powtec.2019.11.058

Abstract: Abstract We prepared hybrid nanocrystal–amorphous solid dispersions (HyNASDs) to enhance the dissolution of a poorly soluble drug, griseofulvin (GF), and elucidated the roles of a surfactant, sodium dodecyl sulfate (SDS), and two polymers, HPC and… read more here.

Keywords: hybrid nanocrystal; solid dispersions; roles surfactant; nanocrystal amorphous ... See more keywords