Depth of Sequencing Plays a Determining Role in the Characterization of Phage Display Peptide Libraries by NGS
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065396
Abstract: Next-generation sequencing (NGS) has raised a growing interest in phage display research. Sequencing depth is a pivotal parameter for using NGS. In the current study, we made a side-by-side comparison of two NGS platforms with… read more here.
Keywords: phage display; display peptide; peptide libraries; characterization ... See more keywords
Analysis of Compositional Bias in a Commercial Phage Display Peptide Library by Next-Generation Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112402
Abstract: The principal presumption of phage display biopanning is that the naïve library contains an unbiased repertoire of peptides, and thus, the enriched variants derive from the affinity selection of an entirely random peptide pool. In… read more here.
Keywords: peptide library; next generation; phage display; display peptide ... See more keywords