Disparities Associated with Discharge Patterns in Firearm-Associated Ocular Trauma.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2023.1467
Abstract: Importance Firearm injuries are associated with devastating visual outcomes. Several studies have demonstrated disparities in trauma care and discharge to rehabilitation and other advanced care facilities (ACFs) due to race and ethnicity and insurance status.… read more here.
Keywords: disposition; trauma; insurance; discharge ... See more keywords
Regulation of Drug Transport Proteins—From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2605
Abstract: Membrane transport proteins are involved in the absorption, disposition, efficacy, and/or toxicity of many drugs. Numerous mechanisms (e.g., nuclear receptors, epigenetic gene regulation, microRNAs, alternative splicing, post‐translational modifications, and trafficking) regulate transport protein levels, localization,… read more here.
Keywords: disposition; transport proteins; transporter; transport ... See more keywords
Liver safety evaluation of endothelin receptor antagonists using HepatoPac®: A single model impact assessment on hepatocellular health, function and bile acid disposition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3805
Abstract: Marketed (bosentan, ambrisentan) and discontinued (sitaxsentan, CI‐1034) endothelin receptor antagonists were examined in the human micropatterned hepatocyte co‐culture (MPCC) model HepatoPac®. Differences across hepatocellular health (cellular adenosine triphosphate/glutathione content), function (urea production/albumin secretion) and taurocholic… read more here.
Keywords: disposition; safety; hepatocellular health; model ... See more keywords
Availability of a final abdominopelvic CT report before emergency department disposition: risk-adjusted outcomes in patients with abdominal pain
Sign Up to like & getrecommendations! Published in 2021 at "Abdominal Radiology"
DOI: 10.1007/s00261-020-02899-4
Abstract: Objective To determine whether availability of a final radiologist report versus an experienced senior resident preliminary report prior to disposition affects major care outcomes in emergency department (ED) patient presenting with abdominal pain undergoing abdominopelvic… read more here.
Keywords: disposition; abdominal pain; radiology; report ... See more keywords
Investigating Intestinal Transporter Involvement in Rivaroxaban Disposition through Examination of Changes in Absorption.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03039-3
Abstract: PURPOSE The involvement of the intestinally expressed xenobiotic transporters P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) have been implicated in rivaroxaban disposition based on in vitro studies, similar to what had previously been proposed… read more here.
Keywords: disposition; examination; rivaroxaban disposition; involvement ... See more keywords
Age-and Region-Dependent Disposition of Raloxifene in Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical research"
DOI: 10.1007/s11095-021-03084-y
Abstract: PURPOSE Raloxifene undergoes extensive glucuronidation in the gastrointestinal (GI) tract and the liver. However, the impact of age on raloxifene disposition has never been studied. The purpose of this paper is to determine glucuronidation and… read more here.
Keywords: oral bioavailability; week; disposition; age ... See more keywords
Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Therapy"
DOI: 10.1007/s12325-019-01075-5
Abstract: Exogenous progesterone is prescribed for a variety of conditions with endogenous progesterone deficiency, e.g. menstrual alterations, primary or secondary infertility or premenopause. To the best of our knowledge, no pharmacogenetic studies have been published in… read more here.
Keywords: disposition; safety; cyp2c9 cyp2c19; safety metabolism ... See more keywords
Suicide screening scales may not adequately predict disposition of suicidal patients from the emergency department
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Emergency Medicine"
DOI: 10.1016/j.ajem.2018.01.087
Abstract: Background Suicide screening scales have been advocated for use in the ED setting. However, it is currently unknown whether patients classified as low‐risk on these scales can be safely discharged from the emergency department. This… read more here.
Keywords: disposition; screening tools; emergency department; emergency ... See more keywords
48 Management and Disposition of Patients with Venous Thromboembolism In Academic Vs. Rural Hospital Populations During the COVID-19 Pandemic
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Emergency Medicine"
DOI: 10.1016/j.annemergmed.2021.07.049
Abstract: Study Objective: While being supported by national societies, management of low-risk venous thromboembolisms (VTEs) in the outpatient setting with direct oral anticoagulant medications (DOACs), has yet to become standard of care. We sought to determine… read more here.
Keywords: disposition; academic settings; management; academic rural ... See more keywords
Disposition sales and stock market liquidity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Financial Markets"
DOI: 10.1016/j.finmar.2019.04.003
Abstract: This paper studies the impact of the disposition effect, which results in uninformed sales when investors realize their capital gains. Market makers should post tighter bid-ask spreads and quote prices that are less sensitive to… read more here.
Keywords: stock market; disposition sales; market liquidity; disposition ... See more keywords
Exchange-traded certificates, education and the disposition effect
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Behavioral and Experimental Finance"
DOI: 10.1016/j.jbef.2020.100456
Abstract: Abstract This study establishes a link between the disposition effect present in the transactions of exchange-trade certificates (ETC), investor education and different dimensions of trading experience. Using transaction-level data of 35,508 individuals from a major… read more here.
Keywords: disposition; disposition effect; exchange; education ... See more keywords