Articles with "disposition metabolism" as a keyword



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The Disposition and Metabolism of Bempedoic Acid, a Potent Inhibitor of ATP Citrate Lyase, in Healthy Human Subjects

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Published in 2023 at "Drug Metabolism and Disposition"

DOI: 10.1124/dmd.122.001142

Abstract: The disposition and metabolism of bempedoic acid, a selective inhibitor of ATP citrate lyase, were examined in healthy male subjects. After a single administration of [14C] bempedoic acid (240 mg, 113 μCi) oral solution, mean… read more here.

Keywords: bempedoic; bempedoic acid; disposition metabolism;