Articles with "disposition modeling" as a keyword



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Target‐mediated drug disposition modeling of an anti‐TFPI antibody (MG1113) in cynomolgus monkeys to predict human pharmacokinetics and pharmacodynamics

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Published in 2021 at "Journal of Thrombosis and Haemostasis"

DOI: 10.1111/jth.15244

Abstract: MG1113 is a human monoclonal antibody of tissue factor pathway inhibitor (TFPI) under development for prophylaxis for hemophilia patients with or without inhibitors against factor VIII products, which have been used for the treatment of… read more here.

Keywords: disposition modeling; antibody; mediated drug; tfpi ... See more keywords