Identification of Substandard Medicines via Disproportionality Analysis of Individual Case Safety Reports
Sign Up to like & getrecommendations! Published in 2017 at "Drug Safety"
DOI: 10.1007/s40264-016-0499-5
Abstract: IntroductionThe distribution and use of substandard medicines (SSMs) is a public health concern worldwide. The detection of SSMs is currently limited to expensive large-scale assay techniques such as high-performance liquid chromatography (HPLC). Since 2013, the… read more here.
Keywords: substandard medicines; individual case; disproportionality analysis; analysis ... See more keywords
Active comparator restricted disproportionality analysis for pharmacovigilance signal detection studies of chronic disease medications: An example using sodium/glucose cotransporter 2 (SGLT2) inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15178
Abstract: INTRODUCTION Disproportionality analysis is a common pharmacovigilance tool to detect safety signals of type 2 diabetes medications from spontaneous drug reporting databases. OBJECTIVE To demonstrate the impact of using the active-comparator restricted disproportionality analysis (ACR-DA),… read more here.
Keywords: disproportionality analysis; comparator; sglt2 inhibitors; aror ... See more keywords
Ear and labyrinth toxicities induced by immune checkpoint inhibitors: a disproportionality analysis from 2014 to 2019.
Sign Up to like & getrecommendations! Published in 2020 at "Immunotherapy"
DOI: 10.2217/imt-2019-0120
Abstract: Aim: We aimed to systematically characterize ear and labyrinth toxicities after immune checkpoint inhibitors (ICIs) initiation. Materials & methods: Data were extracted from the US FDA Adverse Event Reporting System database. Disproportionality analysis including information… read more here.
Keywords: labyrinth toxicities; immune checkpoint; checkpoint inhibitors; disproportionality analysis ... See more keywords
Is Omalizumab Related to Ear and Labyrinth Disorders? A Disproportionality Analysis Based on a Global Pharmacovigilance Database
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DOI: 10.3390/diagnostics12102434
Abstract: Introduction: Asthma is a chronic disease, characterized by reversible airway obstruction, hypersensitivity reactions, and inflammation. Oral corticosteroids are an important treatment option for patients with severe or steroid-resistant asthma. Biologics for asthma are recommended in… read more here.
Keywords: ear labyrinth; disproportionality analysis; related ear; analysis ... See more keywords