Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
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DOI: 10.1016/j.celrep.2018.09.083
Abstract: SUMMARY How mutations in glial fibrillary acidic protein (GFAP) cause Alexander disease (AxD) remains elusive. We generated iPSCs from two AxD patients and corrected the GFAP mutations to examine the effects of mutant GFAP on… read more here.
Keywords: disrupt distribution; human astrocytes; axd astrocytes; mutations gfap ... See more keywords