Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks
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DOI: 10.3389/fncel.2017.00321
Abstract: Ataxia-telangiectasia (A-T) is a rare genetic disorder caused by loss of function of the ataxia-telangiectasia-mutated kinase and is characterized by a predisposition to cancer, pulmonary disease, immune deficiency and progressive degeneration of the cerebellum. As… read more here.
Keywords: disrupted gene; derived cerebellar; gene regulatory; ataxia telangiectasia ... See more keywords