Interrogating PP1 Activity in the MAPK Pathway with Optimized PP1‐Disrupting Peptides
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DOI: 10.1002/cbic.201800541
Abstract: Protein phosphatase‐1 (PP1)‐disrupting peptides (PDPs) are selective chemical modulators of PP1 that liberate the active PP1 catalytic subunit from regulatory proteins; thus allowing the dephosphorylation of nearby substrates. We have optimized the original cell‐active PDP3… read more here.
Keywords: pp1 activity; interrogating pp1; pp1 disrupting; disrupting peptides ... See more keywords