Disruption of the beclin 1/Bcl-2 autophagy regulatory complex promotes longevity in mice
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DOI: 10.1038/s41586-018-0162-7
Abstract: Autophagy increases the lifespan of model organisms; however, its role in promoting mammalian longevity is less well-established1,2. Here we report lifespan and healthspan extension in a mouse model with increased basal autophagy. To determine the… read more here.
Keywords: longevity; beclin; disruption beclin; bcl2 ... See more keywords