Disruption of Crystal Packing in Thieno[2,3-b]pyridines Improves Anti-Proliferative Activity
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DOI: 10.3390/molecules27030836
Abstract: 3-Amino-2-arylcarboxamido-thieno[2,3-b]pyridines have been shown to have anti-proliferative activity, but are also known to have poor solubility. This has been previously proposed to be due to their extensive planarity, which allows for intermolecular stacking and crystal… read more here.
Keywords: proliferative activity; anti proliferative; crystal packing; thieno pyridines ... See more keywords