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Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00285
Abstract: Lanosterol, an amphipathic molecule, was discovered only very recently to effectively hinder the aggregation of the lens proteins and dissolve the extremely stable fibrillar aggregates in cataracts. Here, we combined computational and experimental approaches to…
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Keywords:
aggregation;
peptide;
lanosterol disrupts;
aggregation amyloid ... See more keywords