A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006186
Abstract: Legionella pneumophila, the etiological agent of Legionnaires’ disease, replicates intracellularly in protozoan and human hosts. Successful colonization and replication of this pathogen in host cells requires the Dot/Icm type IVB secretion system, which translocates approximately… read more here.
Keywords: legionella effector; host cytoskeletal; ravk; disrupts host ... See more keywords
SARS-CoV-2 disrupts host gene networks: Unveiling key hub genes as potential therapeutic targets for COVID-19 management
Sign Up to like & getrecommendations! Published in 2024 at "Computers in biology and medicine"
DOI: 10.21203/rs.3.rs-4214583/v1
Abstract: PURPOSE Although the end of COVID-19 as a public health emergency was declared on May 2023, still new cases of the infection are reported and the risk remains of new variants emerging that may cause… read more here.
Keywords: sars cov; cov disrupts; disrupts host; host gene ... See more keywords
Mechanism by which porcine transmissible gastroenteritis virus disrupts host innate immunity
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1675572
Abstract: Innate immune evasion is a critical aspect of viral infections, as it disrupts the host’s defense mechanisms.The innate immune system, as the primary defense against pathogens, detects pathogen-associated molecular patterns (PAMPs) via pattern recognition receptors… read more here.
Keywords: transmissible gastroenteritis; host; porcine transmissible; disrupts host ... See more keywords