Quartz disrupts iron homeostasis in alveolar macrophages to impact a pro-inflammatory effect.
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DOI: 10.1021/acs.chemrestox.8b00301
Abstract: The biological response of bronchial epithelial cells to particles is associated with a sequestration of cell metal by the particle surface and a subsequent disruption in host iron homeostasis. The macrophage is that cell type… read more here.
Keywords: homeostasis; iron homeostasis; silica; exposure ... See more keywords