Dissection of α4β7 integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β7 antibodies
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DOI: 10.1038/s41598-020-70111-0
Abstract: Integrin activation is associated with conformational regulation. In this study, we developed a system to evaluate conformational changes in α4β7 integrin. We first inserted the PA tag into the plexin-semaphorin-integrin (PSI) domain of β7 chain,… read more here.
Keywords: integrin regulation; regulation rap1; conformation; rap1 ... See more keywords