Functional dissection of N-terminal nuclear trafficking signals of SETDB1
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DOI: 10.3389/fcell.2022.1069765
Abstract: SETDB1 is a histone H3-lysine 9-specific methyltransferase that fulfills epigenetic functions inside the nucleus; however, when overexpressed, SETDB1 majorily localizes in the cytoplasm. SETDB1 has a single nuclear-localization-signal (NLS) motif and two successive nuclear-export-signal (NES1… read more here.
Keywords: gfp setdb1; localization; setdb1; dissection terminal ... See more keywords