Clinical Significance of Interferon-&ggr; Neutralizing Autoantibodies Against Disseminated Nontuberculous Mycobacterial Disease
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Infectious Diseases"
DOI: 10.1093/cid/cix996
Abstract: Background Interferon-γ neutralizing autoantibodies (nIFNγ-autoAbs) are reported in patients with disseminated nontuberculous mycobacteria (NTM) infection and may function by increasing the infection risk. Notwithstanding, the prevalence of nIFNγ-autoAbs as well as the clinical presentation, diagnosis,… read more here.
Keywords: disseminated nontuberculous; nifn autoabs; infection; ntm infection ... See more keywords
Disseminated Nontuberculous Mycobacterial Infection in a Patient with Anti-IFN-γ Autoantibodies.
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DOI: 10.18926/amo/55594
Abstract: We treated a 72-year-old Japanese female with sustained high fever and overall body exhaustion. An infectious liver cyst and right lung pneumonia were suspected causes. Hepatic cystectomy and various antibiotics did not resolve symptoms. Pneumonia… read more here.
Keywords: disseminated nontuberculous; anti ifn; mycobacterial infection; nontuberculous mycobacterial ... See more keywords
Anti-interferon-γ Antibody-seropositive Disseminated Nontuberculous Mycobacterial Infection Mimicking POEMS and TAFRO Syndromes
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DOI: 10.2169/internalmedicine.8366-21
Abstract: Disseminated nontuberculous mycobacterial infection (DNTM) is typically observed in immunocompromised hosts. Recently, it has been reported that healthy individuals with serum neutralizing autoantibodies for interferon (IFN)-γ can also develop DNTM. We herein report a case… read more here.
Keywords: nontuberculous mycobacterial; mycobacterial infection; disseminated nontuberculous; antibody seropositive ... See more keywords
Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
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DOI: 10.3201/eid2703.202359
Abstract: Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug,… read more here.
Keywords: disseminated nontuberculous; nontuberculous mycobacteria; treatment disseminated; treatment ... See more keywords