Dissociated response and clinical benefit in patients treated with nivolumab monotherapy
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DOI: 10.1007/s10637-021-01077-7
Abstract: Immune checkpoint inhibitors (ICIs) are effective for previously treated patients with advanced non-small cell lung cancer (NSCLC). However, an unconventional response pattern is sometimes encountered. A dissociated response (DR), characterized by some lesions shrinking and… read more here.
Keywords: nivolumab monotherapy; response; dissociated response; previously treated ... See more keywords
Dissociated response among multiple metastatic lesions in the patients with metastatic renal cell carcinoma treated with immune checkpoint inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyac144
Abstract: INTRODUCTION Metastases from renal cell carcinoma develop in various organs. However, the breadth of discrepancy in response to immune checkpoint inhibitors across tumor sites within the same individual remains unclear. PATIENTS AND METHODS We reviewed… read more here.
Keywords: dissociated response; cell carcinoma; response; renal cell ... See more keywords
Dissociated Response in Metastatic Cancer: An Atypical Pattern Brought Into the Spotlight With Immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.566297
Abstract: When evaluating metastatic tumor response to systemic therapies, dissociated response is defined as the coexistence of responding and non-responding lesions within the same patient. Although commonly observed on interim whole-body imaging, the current response criteria… read more here.
Keywords: immunotherapy; response; pattern; response metastatic ... See more keywords