Solution‐Based Determination of Dissociation Constants for the Binding of Aβ42 to Antibodies
Sign Up to like & getrecommendations! Published in 2019 at "ChemistryOpen"
DOI: 10.1002/open.201900167
Abstract: Abstract Amyloid β‐peptides (Aβ) play a major role in the pathogenesis of Alzheimer's disease. Therefore, numerous monoclonal antibodies against Aβ have been developed for basic and clinical research. The present study applied fluorescence based analytical… read more here.
Keywords: determination dissociation; solution based; based determination; dissociation ... See more keywords
The stoichiometric dissociation constants of carbonic acid in seawater brines from 298 to 267 K
Sign Up to like & getrecommendations! Published in 2018 at "Geochimica et Cosmochimica Acta"
DOI: 10.1016/j.gca.2017.09.037
Abstract: Abstract The stoichiometric dissociation constants of carbonic acid ( K 1 C ∗ and K 2 C ∗ ) were determined by measurement of all four measurable parameters of the carbonate system (total alkalinity, total… read more here.
Keywords: stoichiometric dissociation; seawater; constants carbonic; carbonic acid ... See more keywords
Novel 1,4-naphthoquinone N-aroylthioureas: Syntheses, crystal structure, anion recognition properties, DFT studies and determination of acid dissociation constants
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.08.054
Abstract: Abstract In this paper, five novel 1,4-naphthoquinone N-aroylthiourea derivatives were synthesized, by the reaction of 2,3-diaminonaphthalene-1,4-dione and aroylisothiocyanates, in excellent yield (88–96%) and characterized by using FT-IR, 1H/13C NMR and HRMS. In addition, the molecular… read more here.
Keywords: novel naphthoquinone; acid dissociation; structure; dissociation constants ... See more keywords
Preorganized PSP Ligands Yield Monomeric Cu(I) Complexes with Subzeptomolar Cu(I) Dissociation Constants.
Sign Up to like & getrecommendations! Published in 2019 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.9b00965
Abstract: Unraveling the function of biological copper (Cu) requires tools that can selectively recognize and manipulate this trace nutrient within the complex chemical environment of biological systems. Increasing evidence suggests that cells maintain an exchangeable pool… read more here.
Keywords: yield monomeric; psp ligands; preorganized psp; dissociation ... See more keywords
Potentiometric Determination of Acid Dissociation Constants (pK a) for an Anticancer Pyrrole-Imidazole Polyamide.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00348
Abstract: To optimize the pharmacological properties of an anticancer pyrrole-imidazole (Py-Im) polyamide (PIP-1), we characterized the acid dissociation constants of PIP-1, three other structurally related hairpin-shaped polyamides, and a cyclic polyamide bearing the same core sequence… read more here.
Keywords: dissociation constants; pyrrole imidazole; dissociation; acid dissociation ... See more keywords
Determination of acid dissociation constants of Alizarin Red S, Methyl Orange, Bromothymol Blue and Bromophenol Blue using a digital camera
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/c9ra10568a
Abstract: Acid dissociation constants (pKa) are important parameters for the characterization of organic and inorganic compounds. They play a crucial role in different physical, chemical, and biological studies. Herein, we introduce a new approach for the… read more here.
Keywords: blue; dissociation; acid dissociation; alizarin red ... See more keywords
Simultaneous Determination of the Acid Dissociation Constants of Phenolics by Multivariate Analysis of pH and Ultraviolet-Visible Spectrophotometric Measurements
Sign Up to like & getrecommendations! Published in 2021 at "Analytical Letters"
DOI: 10.1080/00032719.2021.1880424
Abstract: Abstract In the development of new commercial products in the pharmaceutical and food industries, acid dissociation constant (Ka) values of active and inactive ingredients are important factors for the estimation of the biological activity. In… read more here.
Keywords: simultaneous determination; dissociation; acid dissociation; mcr als ... See more keywords
Current estimates of K1* and K2* appear inconsistent with measured CO2 system parameters in cold oceanic regions
Sign Up to like & getrecommendations! Published in 2020 at "Ocean Science"
DOI: 10.5194/os-16-847-2020
Abstract: Abstract. Seawater absorption of anthropogenic atmospheric carbon dioxide ( CO2 ) has led to a range of changes in carbonate chemistry, collectively referred to as ocean acidification. Stoichiometric dissociation constants used to convert measured carbonate… read more here.
Keywords: stoichiometric dissociation; system; co2; co2 system ... See more keywords