Kinetic inequivalence between α and β subunits of ligand dissociation from ferrous nitrosylated human haptoglobin:hemoglobin complexes. A comparison with O2 and CO dissociation.
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DOI: 10.1016/j.jinorgbio.2020.111272
Abstract: Haptoglobin (Hp) counterbalances the adverse effects of extra-erythrocytic hemoglobin (Hb) by trapping the αβ dimers of Hb in the bloodstream. In turn, the Hp:Hb complexes display Hb-like reactivity. Here, the kinetics of NO dissociation from… read more here.
Keywords: dissociation ferrous; hemoglobin; dissociation; ferrous nitrosylated ... See more keywords