Articles with "dissolution dispersion" as a keyword



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Physicochemical and biopharmaceutical characterization of celecoxib nanoparticle: Avoidance of delayed oral absorption caused by impaired gastric motility

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Published in 2018 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.09.051

Abstract: ABSTRACT The present study aimed to develop a celecoxib (CEL) nanoparticle with improved dissolution/dispersion and consistent absorption even in the presence of impaired gastric motility. CEL was pulverized by a wet‐milling with hydroxypropyl cellulose (HPC),… read more here.

Keywords: absorption; dissolution dispersion; nanoparticle; gastric motility ... See more keywords