Synchronization of Cocrystal Dissolution and Drug Precipitation to Sustain Drug Supersaturation.
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DOI: 10.1021/acs.molpharmaceut.2c00122
Abstract: A graphical analysis of both drug and coformer concentrations contributed by dissolving cocrystals is presented in the context of a simplified cocrystal phase diagram. The conceptual basis and analysis identify parameters that control cocrystal dissolution-drug… read more here.
Keywords: dissolution drug; drug supersaturation; drug; cocrystal dissolution ... See more keywords