Modified sprouted rice for modulation of curcumin crystallinity and dissolution enhancement by solid dispersion
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-018-0393-5
Abstract: Sprouted grains, which is a natural polysaccharide, is the subject of increasing scientific interest due to many benefits for human health. The aim of the present work was to develop sprouted rice (SR) as a… read more here.
Keywords: dissolution enhancement; crystallinity; dissolution; sprouted rice ... See more keywords
Critical Excipient Properties for the Dissolution Enhancement of Phenytoin
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DOI: 10.1021/acsomega.9b02383
Abstract: Solubility-enhancing amorphous solid dispersions can aid in the oral delivery of hydrophobic, poorly soluble drugs. Effective solid dispersion excipients enable high supersaturation drug concentrations over biologically relevant time scales. The critical characteristics of an excipient… read more here.
Keywords: excipient properties; properties dissolution; solid dispersions; phenytoin ... See more keywords
Efavirenz Dissolution Enhancement IV—Antisolvent Nanocrystallization by Sonication, Physical Stability, and Dissolution
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DOI: 10.1208/s12249-017-0781-6
Abstract: Efavirenz is a fundamental drug in the HIV therapy; however, it has a low bioavailability due to low water solubility. Particle nanonization should enhance its dissolution and therefore its bioavailability. Nanocrystallization is a promising technique… read more here.
Keywords: efavirenz dissolution; zeta potential; particle; nanocrystallization ... See more keywords
Solubility and Dissolution Enhancement of Sulfasalazine by Solid Dispersion Technique
Sign Up to like & getrecommendations! Published in 2018 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2018.00237.8
Abstract: The solubility behavior of drug remains one of the most challenging aspects in formulation development. Most NCE are poorly water soluble, drug not well absorbed after oral administration. Solid dispersion is an increasingly important approach… read more here.
Keywords: solid dispersion; sulfasalazine; solubility; dissolution enhancement ... See more keywords