Prediction of the Long-Term Dissolution Performance of an Immediate-Release Tablet Using Accelerated Stability Studies.
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DOI: 10.1016/j.xphs.2018.10.025
Abstract: A slowdown in dissolution performance has been observed for an immediate release tablet formulation during long-term stability testing. The slowdown was successfully predicted using an accelerated stability study in which the dissolution was tested over… read more here.
Keywords: dissolution performance; stability; long term; accelerated stability ... See more keywords
Pharmaceutical cocrystals of naringenin with improved dissolution performance
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DOI: 10.1039/c8ce00341f
Abstract: Naringenin (NAR), a natural flavanone compound, has received increasing attention in recent years due to its diverse pharmacological activities. However, this bioflavonoid shows poor solubility and therefore is difficult to absorb on oral ingestion. To… read more here.
Keywords: dissolution performance; naringenin improved; improved dissolution; cocrystals naringenin ... See more keywords
Role of Cyclodextrins and Drug Solid State Properties on Flufenamic Acid Dissolution Performance from Tablets
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DOI: 10.3390/pharmaceutics14020284
Abstract: Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence. Different FFA batches, obtained by different suppliers, showed different powder characteristics (particle size, shape… read more here.
Keywords: dissolution; solid state; drug; dissolution performance ... See more keywords