Dissolution and permeability properties of co-amorphous formulations of hydrochlorothiazide.
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DOI: 10.1016/j.xphs.2020.04.008
Abstract: A biopharmaceutics classification system class IV drug, hydrochlorothiazide (HCT), was combined with co-formers of L-and D-arginine (ARG) and sodium lauryl sulphate (SLS) by cryomilling in 1:1 molar ratio. Co-amorphization was observed with L- and D-ARG.… read more here.
Keywords: permeability properties; amorphous formulations; permeability; properties amorphous ... See more keywords