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   Articles with "dissolution profiles" as a keyword



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Variability in content and dissolution profiles of MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users?

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recommendations! Published in 2019 at "Drug testing and analysis"

DOI: 10.1002/dta.2605

Abstract: 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) tablets are widely used recreationally, and not only vary in appearance, but also in MDMA content. Recently, the prevalence of high-content tablets is of concern to public health authorities. To compare UK… read more here.

Keywords: content; variability; dissolution profiles; mdma content ... See more keywords
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Estimators and confidence intervals of f2 using bootstrap methodology for the comparison of dissolution profiles.

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recommendations! Published in 2021 at "Computer methods and programs in biomedicine"

DOI: 10.1016/j.cmpb.2021.106449

Abstract: BACKGROUND AND OBJECTIVES The most widely used method to compare dissolution profiles is the similarity factor f2. When this method is not applicable, the confidence interval of f2 using bootstrap methodology has been recommended instead.… read more here.

Keywords: methodology; confidence; dissolution profiles; bootstrap ... See more keywords
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Prediction of dissolution profiles by non-destructive NIR spectroscopy in bilayer tablets.

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recommendations! Published in 2019 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2019.05.022

Abstract: This study describes how near infrared (NIR) spectroscopy can be used to predict the dissolution of bilayer tablets as a non-destructive approach. Tablets in this study consist of two active pharmaceutical ingredients (APIs) physically separated… read more here.

Keywords: bilayer tablets; non destructive; dissolution profiles; nir spectroscopy ... See more keywords
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In Vitro Dissolution Profiles of Two Diltiazem Tablet Formulations and a Compounded Capsule Formulation: A Comparative Study

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recommendations! Published in 2017 at "Dissolution Technologies"

DOI: 10.14227/dt240217p38

Abstract: The dissolution test is usually employed to evaluate the performance of drug products. In this study, we compared the in vitro dissolution profiles of two diltiazem hydrochloride tablet formulations with that of a diltiazem hydrochloride… read more here.

Keywords: formulation; drug; dissolution profiles; dissolution ... See more keywords
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Comparative dissolution profiles of two anti-emetic delayed release dosage forms of doxylamine and pyridoxine: Xonvea® tablets vs. Cariban® capsules.

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recommendations! Published in 2022 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202206_29081

Abstract: OBJECTIVE Nausea and vomiting of pregnancy is a common disease that affects many women suffering from mild to severe symptoms. Amongst the different treatments, a fixed dose combination of doxylamine and pyridoxine has been proven… read more here.

Keywords: dissolution; dosage forms; release; cariban capsules ... See more keywords
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In Silico Prediction of Plasma Concentrations of Fluconazole Capsules with Different Dissolution Profiles and Bioequivalence Study Using Population Simulation

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recommendations! Published in 2019 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics11050215

Abstract: A biowaiver is accepted by the Brazilian Health Surveillance Agency (ANVISA) for immediate-release solid oral products containing Biopharmaceutics Classification System (BCS) class I drugs showing rapid drug dissolution. This study aimed to simulate plasma concentrations… read more here.

Keywords: bioequivalence; population simulation; dissolution profiles; simulation ... See more keywords
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A Critical Overview of FDA and EMA Statistical Methods to Compare In Vitro Drug Dissolution Profiles of Pharmaceutical Products

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recommendations! Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13101703

Abstract: A drug dissolution profile is one of the most critical dosage form characteristics with immediate and controlled drug release. Comparing the dissolution profiles of different pharmaceutical products plays a key role before starting the bioequivalence… read more here.

Keywords: drug dissolution; dissolution profiles; pharmaceutical products; dissolution ... See more keywords
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Dissolution profiles of partially purified bromelain from pineapple cores [Ananas comosus (L.) Merr] encapsulated in glutaraldehyde-crosslinked chitosan

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recommendations! Published in 2018 at "journal of applied pharmaceutical science"

DOI: 10.7324/japs.2018.81003

Abstract: To avoid degradation in the stomach, the proteolytic enzyme bromelain must be encapsulated in glutaraldehydecrosslinked chitosan (CGF) hydrogels, which can maintain the activity of bromelain until it reaches the intestine. In this study, we isolated… read more here.

Keywords: bromelain; purified bromelain; profiles partially; dissolution profiles ... See more keywords