Characteristics of immune induction by transcutaneous vaccination using dissolving microneedle patches in mice.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.120563
Abstract: Transcutaneous immunization (TCI) is an appealing vaccination method. Compared with conventional injectable immunization, TCI is easier and less painful. We previously developed a dissolving microneedle (MN) patch and demonstrated that TCI using MN patches demonstrates… read more here.
Keywords: dissolving microneedle; tci using; immune induction; vaccination ... See more keywords
Enhanced Transdermal Delivery by Combined Application of Dissolving Microneedle Patch on Serum-Treated Skin.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00111
Abstract: Dissolving microneedle (DMN), a transdermal drug delivery system in which drugs are encapsulated in a biodegradable polymeric microstructure, is designed to dissolve after skin penetration and release the encapsulated drugs into the body. However, because… read more here.
Keywords: dissolving microneedle; delivery; skin; serum ... See more keywords
A tearable dissolving microneedle system for shortening application time
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2019.1583645
Abstract: ABSTRACT Objectives: A tearable dissolving microneedle system (TD-MN system) was developed for shortening the time required to administer drugs into the skin through the dissolving microneedles. Methods: TD-MN system consisted of an array of tearable… read more here.
Keywords: dissolving microneedle; microneedle system; system; tearable dissolving ... See more keywords
Feasibility of Enhancing Skin Permeability of Acyclovir through Sterile Topical Lyophilized Wafer on Self-Dissolving Microneedle-Treated Skin
Sign Up to like & getrecommendations! Published in 2022 at "Dose-Response"
DOI: 10.1177/15593258221097594
Abstract: Acyclovir is an antiviral drug that is frequently prescribed for the herpes virus. However, the drug requires frequent dosing due to limited bioavailability (10–26.7%). The rationale of the present study was to develop a self-dissolving… read more here.
Keywords: dissolving microneedle; self dissolving; acyclovir; wafer ... See more keywords
Development of a Novel Self-Dissolving Microneedle-Assisted Percutaneous Delivery System of Diacerein through Solid Dispersion Gel: Solubility Enhancement, Proof of Anti-inflammatory Activity and Safety.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug delivery"
DOI: 10.2174/1567201819666220629123058
Abstract: BACKGROUND Diacerein, an osteoarthiritis drug, experiences slow topical permeation due to limited solubility. Additionally it shows laxative effect due to acid/base hydrolysis of drug in colon. OBJECTIVE Diacerein solubility was improved to increase percutaneous drug… read more here.
Keywords: dissolving microneedle; solid dispersion; diacerein; solubility ... See more keywords